The Fort Qu'Appelle Indian [Indigenous] Hospital was operated by the Department of Indian Affairs from 1936-1996. In 1996, ownership transferred to the Touchwood File Hills Qu'Appelle Tribal Council who operated it until 2004, when it was replaced by the All Nations' Healing Hospital. In 2014, the Fort Qu'Appelle Indian [Indigenous] Hospital building was demolished.

The "Great White Plague" was the name used to describe tuberculosis. To fight the highly contagious disease the Saskatchewan Anti-Tuberculosis League was formed in 1911. Under its auspices Fort Qu'Appelle Sanatorium, was opened in 1917 to provide rest and fresh air. But the cure was long and tedious; few could afford to remain until they were healed. So in 1929, through the League's urging, Saskatchewan was the first province to make the care and treatment of tuberculosis free of charge. In 1987, with the closure of the sanatoriums, the League is reorganized into the Saskatchewan Lung Association.