Melville Pastoral Charge was formed as a new United Church charge in 1925, containing First United Church, in Melville. This congregation is generally considered the first Local Union formed in Canada, dating back to 1908 and coinciding with the Basis of Union, which eventually lead to the creation of the United Church of Canada. Original members included Methodists, Baptists, Congregationalists, and Presbyterians.

Milestone Pastoral Charge was formed as a United Church charge in 1925, part of Weyburn Presbytery, consisting of the Milestone preaching appointment. Between 1951 and 1958, the charge joined with Lang Pastoral Charge to create the joint Lang-Milestone Pastoral Charge. Between 1974 and ca.1986, appointments included Parry, as well as Lang and Milestone.

On January 1, 2013, the joint charge amalgamated with Rouleau-Wilcox Pastoral Charge to create the new Soo Line Pastoral Charge.

Moose Jaw Grandview Pastoral Charge was formed after the dissolution of the joint Moose Jaw Trinity-Grandview Pastoral Charge, in June 2001. The charge officially closed on June 30, 2012.

Moose Jaw Minto Pastoral Charge was formed as a new United Church charge in 1925, from what had previously been the Presbyterian Moose Jaw Minto Pastoral Charge.

Moose Jaw St. Andrew's Pastoral Charge was formed as a new United Church charge in 1925, from what had previously been the Presbyterian Moose Jaw St. Andrew's Pastoral Charge.

Moose Jaw Trinity Pastoral Charge was formed as a new United Church charge in 1925, from what had previously been the Moose Jaw Wesley Methodist Circuit. Around 1960, Grandview United Church joined the charge, which was renamed Trinity-Grandview Pastoral Charge. On June 30, 2001, the joint-charge was officially dissolved and the congregations formed separate charges, including the re-formed Trinity Pastoral Charge.

Moose Jaw Zion Pastoral Charge was formed as a new United Church charge in 1925, from what had previously been the Moose Jaw Zion Methodist Circuit.

Moosomin Pastoral Charge was formed as a new United Church charge in 1925, containing preaching points at Moosomin (Bethel United Church) and Orangeville, which was soon after reassigned to Wapella Pastoral Charge. Additional points included: Fleming (until closure, January 1, 1985).

Prior to Union, there had been Methodist and Presbyterian congregations in the area. The churches amalgamated in 1925, in what had been previously the Moosomin Methodist Church (built in 1889, dedicated 1890), and the Presbyterian St. Andrew's Church building (dedicated 1903, located on the site of an earlier Presbyterian Church, built 1884) was sold soon after.