Regina St. James Pastoral Charge was formed as the new United Church Regina North charge in 1925, from what had previously been the Presbyterian North Regina Condie Mission Field. The church was listed as part of Regina Chalmers Pastoral Charge, ca.1932, and later part of Regina Rosemont Pastoral Charge, ca.1936 through the early 1940s. By 1946, Regina North Pastoral Charge was re-established (but listed as vacant).

Regina Carmichael Pastoral Charge was formed as a new United Church charge in 1925, containing the Carmichael United Church preaching point. The church had been originally formed (in 1925) by congregations at the former Wesley Methodist Church and Carmichael Presbyterian Church, named after a former Presbyterian Superintendent of Missions, Dr. James Carmichael. The charge closed June 30, 1995.

Regina St. John's Pastoral Charge was formed around 1954, part of Regina Presbytery and containing the new St. John's United Church, built at McTavish Street and Fourth Avenue, Regina. The decision to have a new building had resulted from a presbytery Church Extension Committee survey (ca.1951) that determined the district of the city required facilities not available at the existing Sixth Street United Church. The first service in the new St. John's United Church was held November 14, 1954. The pastoral charge closed June 30, 1999.

Regina Metropolitan Pastoral Charge was formed as a new United Church charge in 1925, containing the preaching point Metropolitan United Church, formerly Metropolitan Methodist Church.

In 1951, Knox United Church amalgamated with Metropolitan United Church, to become Knox-Metropolitan United Church (and Pastoral Charge), located on the site of the former Metropolitan United Church, at the corner of Victoria Avenue and Lorne Street.

Regina Rosemont Pastoral Charge was formed as a new United Church charge in 1925, from what had previously been a Methodist field. Around 1932, Rosemont United was listed as part of Regina Chalmers Pastoral Charge (with St. James and Chalmers United) but it was re-established as a separate charge by 1936, containing Rosemont, Estlin, St. James and Wascana United Churches. Other points were moved around the 1940s and Rosemont formed a joint-charge with Wascana, ca.1951 until about 1953, when they returned to separate charges. On September 30, 2012, Rosemont Pastoral Charge closed.

Regina Chalmers Pastoral Charge was formed as a new United Church charge in 1925, from what had previously been a Presbyterian field. Around 1932, it consisted of Chalmers, Rosemont and St. James congregations but these were reorganized by 1936, with Chalmers listed as under Settlement House, until the early 1940s. The Pastoral Charge was later re-established ca.1946 and eventually closed, June 30, 1994.

Wascana Presbytery was one of the 7 presbyteries of Saskatchewan Conference created in 2000. It was initially comprised of pastoral charges from the former Regina Presbytery. In January 2019, as part of a larger restructuring of the United Church of Canada, Wascana Presbytery was combined with Saskatchewan Conference and the other remaining presbyteries to become Region 4.

Saskatchewan Anti-Tuberculosis Commission, often mistakenly called the Royal Commission on Tuberculosis set out to "to enquire into the question of tuberculosis in Saskatchewan, and to recommend...measures to efficiently deal with the problem" (Report of the Saskatchewan. Anti-Tuberculosis Commission, A.B. Cook, 1922).

Knox-Metropolitan Pastoral Charge was formed after the Knox and Metropolitan United Church congregations amalgamated to form Knox-Metropolitan United Church, on the site of the (former) Metropolitan United Church, at the corner of Victoria Avenue and Lorne Street.