The United Church of Canada was created in 1925, from the union of Presbyterian, Methodist, Congregationalist and Local Union churches. The women’s organizations from the uniting denominations at the time included: the Canada Congregational Woman's Board of Missions (mostly in eastern Canada, since 1886); the Women’s Missionary Society of the Methodist Church (founded 1876); the Woman's Missionary Society of the Presbyterian Church in Canada, Eastern Division (founded 1825) and Western Division (founded 1876); along with their various corresponding regional and local units. Soon after union, these became national, regional and local units of the United Church of Canada Woman’s Missionary Society (W.M.S.).

The new Society had its first annual meeting in 1926. Like the earlier societies, it brought the message of missions before the entire community of the Church, while offering financial support and personnel to its own wide mission programme.

In 1962, United Church W.M.S. and W.A. organizations across the country amalgamated to form the United Church Women (U.C.W.). Presbyterial and local groups developed along similar lines to national bodies, becoming local and presbyterial U.C.W. units in January 1962.

Nipawin Pastoral Charge was originally formed as a United Church Mission Field, in 1925, which soon became an aid-receiving Pastoral Charge (ca. 1926), part of Prince Albert Presbytery. Early preaching points included Nipawin, Codette, Sunny Brook and Moose Plains. By 1932, the latter two had been replaced by Dartmoor and Elkhorn. As of 1962, the charge consisted of Nipawin, Codette and Elkhorn, though the latter point would eventually drop and by the early 1990s, the charge would be re-named Nipawin-Codette Pastoral Charge. On January 1, 2006, Nipawin-Codette amalgamated with Torch River to form Bridging Waters Pastoral Charge.

Canora Ruthenian (later Ukranian) Pastoral Charge was formed as an augmented United Church charge in 1925, part of Kamsack Presbytery and consisting of appointments at Canora (St. Stephen's), Gorlitz, Rhein, Hyas, Hampton, Norquay, and White Sands. By 1940, Hyas had moved to Pelly Pastoral Charge and points at Bear Stream, Danbury, Glen Elder, Kamsack, and Rama had been added. As of 1962, only St. Stephen's (Canora), Gorlitz and Swan Plain remained in the charge -- which appears to have closed around 1964.

Lumsden Pastoral Charge was formed as a new United Church charge in 1925, part of Regina Presbytery and consisting of preaching points at Lumsden (St. Andrew's), Forest and Wascana. Predecessors included Forest Rural [Presbyterian] Church (from ca.1880s, in what was then Carssdale, SK), Lumsden St. Andrew's Presbyterian Church (ca.1890s?), Wascana Rural [Methodist] Church (ca.1888), and Lumsden Wesley Methodist Church (ca.1897). The congregation at Forest amalgamated with Lumsden in 1957 and Wascana Rural closed in 1961, with some of that congregation also joining Lumsden. Around 1970, Craven was added to the Pastoral Charge, though this church eventually closed, December 31, 1991. The Pastoral Charge remained (consisting of St. Andrew's United Church) through the 1990s and moved from Regina Presbytery to the new Wascana Presbyery, in 2000. As of 2019, the charge became part of Living Skies Regional Council, along with other Saskatchewan charges remaining.

Herschel Pastoral Charge was formed as a new United Church charge in 1925, part of Kindersley Presbytery. By 1926, it consisted of preaching points at Herschel, Winona, and Spring Lake. In the 1930s, Winona left the charge, while Wiggins and Kingsland joined it. Sometime between 1946 and 1951, the charge joined with Fiske to form Herschel-Fiske Pastoral Charge, with points at Anglia, Fiske, Herschel, and McGee. Around the mid-1950s, the name had returned to Herschel Pastoral Charge, as of 1962, made up of Herschel, Anglia and Stanraer. Eventually, only the Herschel congregation was left and, as of September 15, 2018, Herschel Pastoral Charge itself officially closed.

Fiske Pastoral Charge was formed as a new United Church charge in 1925, part of Kindersley Presbytery, with points at Fiske, McGee, Oscaloosa and Spring Valley (the latter was not listed in the charge by 1926). Between 1946 and 1951, the charge joined with Herschel to form Herschel-Fiske Pastoral Charge, with points at Anglia, Fiske, Herschel, and McGee. Fiske appears to have closed around the mid-1950s, with the remainder continuing as Herschel Pastoral Charge (made up of Herschel, Anglia and Stanraer, by 1962).