Nokomis Pastoral Charge was formed as a new United Church charge in 1925, containing the preaching points at Nokomis and Richfarms. Later additions included Saline (ca.1936), and Rowanville (ca.1940). By 1946, Richfarms had moved to Lockwood Pastoral Charge and the only points listed in Nokomis Pastoral Charge were Duff, Lorlie and Nokomis. As of 1951, the points at Duff and Lorlie had moved to Pheasant Forks Pastoral Charge and Nokomis Pastoral Charge consisted of Richfarms (again) and Lockwood. By 1962, Richfarms was no longer listed in the charge.

Around 1977, Nokomis and Govan amalgamated into the new Nokomis-Govan Pastoral Charge, with points at Duval, Govan, Lockwood and Nokomis. Lockwood closed June 30, 1981, and Duval closed July 1, 2000. On January 1, 2004, the remaining Nokomis and Govan preaching points divided: Govan joined Semans-Raymore-Punnichy to created the new Crossroads Pastoral Charge; Nokomis amalgamated with Lanigan Pastoral Charge (containing Knox United Church, Lanigan), creating Lanigan-Nokomis Pastoral Charge.

Kennedy Pastoral Charge was formed as a new United Church charge in 1925, part of Qu'Appelle Presbytery. Around 1926, preaching points High View, Fletwode, and Fish Lake were added to the charge. By 1951, Golden Plain, Poplar Grove, and Langbank were also included, under the re-named Kennedy-Langbank Pastoral Charge. Around the 1970s, the name changed back to Kennedy Pastoral Charge. By the early 1990s, Highview was no longer listed and, as of 1992, only Kennedy and Langbank remained in the charge.

Brora Pastoral Charge was formed as a new United Church charge in 1925, part of Regina Presbytery and consisting of Brora, Tregarva and Rose Plain appointments. Balgonie joined the charge around 1965 and both Brora and Balgonie points moved to Regina St. Aidan's Pastoral Charge by 1970. Brora Pastoral Charge was re-established around 1973, with ministry supplied from Regina Rosemont.

The charge was officially closed on June 28, 2015.

Moose Jaw Grandview Pastoral Charge was formed after the dissolution of the joint Moose Jaw Trinity-Grandview Pastoral Charge, in June 2001. The charge officially closed on June 30, 2012.

Craik Pastoral Charge was formed as a new United Church charge in 1925, part of Regina Presbytery and containing preaching points at Craik and Rose Hill. The charge has also included Aylesbury, Foxbury (ca.1951), Holdfast, and Penzance. Aylesbury United Church was closed June 30, 1999. Holdfast United Church was closed March 11, 2009.

Francis Pastoral Charge was formed as a new United Church charge in 1925, containing preaching points at Francis and Pleasant View. The charge closed June 1, 2007.

Regina Knox Pastoral Charge was formed as a new United Church charge in 1925, containing the preaching point Knox United Church, formerly Knox Presbyterian Church. The previous Presbyterian congregation dated back to around 1882. It built a church in 1885, at the corner of Scarth Street and 11th Avenue, and a later replacement in 1905.

In 1951, Knox United Church amalgamated with Metropolitan United Church, to become Knox-Metropolitan United Church (and Pastoral Charge), located on the site of the former Metropolitan United Church, at the corner of Victoria Avenue and Lorne Street.

Regina Westminster Pastoral Charge was formed as a new United Church charge in 1925, including Westminster United Church, itself an amalgamation of Westminster Presbyterian Church (at 3025 - 13th Avenue) and the nearby Fourteenth Avenue Methodist Church (in a temporary building on the southwest corner of 14th Avenue and Retallack Street). These congregations had originated from outreach efforts by the downtown Knox Presbyterian Church and Metropolitan Methodist Church and, in May 1925, they had combined their congregations, in the formerly Presbyterian building.

Yellow Grass Pastoral Charge was formed as a new United Church charge in 1925, part of Weyburn Presbytery and consisting of Yellow Grass United Church. Previously, the church had been a local union since October 1922, when Yellow Grass Methodist and Knox Presbyterian Churches joined together. Later additions to the United Church charge included preaching points at Lewvan and Colfax, as well as Trossachs (moved from Radville Pastoral Charge, July 1, 1985). Colfax was closed in 1984, Lewvan in 1988.

The charge was designated a shared ministry, as of August 27, 2003, under the name Yellow Grass-Trossachs United Lutheran Partnership. After the closure of the Trossachs preaching place, the charge was re-named Yellow Grass United Lutheran Partnership, on August 29, 2007.

Regina Heritage Pastoral Charge was established January 1, 1984, from a preaching point previously part of Regina St. James Pastoral Charge.

Big River Pastoral Charge was originally formed in 1925, as the United Church's Eldred Mission Field, part of Prince Albert Presbytery and containing preaching points at Eldred and Big River. It was listed as an aid-receiving Pastoral Charge in 1926. By 1932, the name had changed to Big River Pastoral Charge, with points at Big River, Eldred and Sturgeon Heights. As of 1936, the charge included Black Duck, De Laronde, Reed and Stoney Lake. South Stoney and Swanston were also added ca.1940. By 1962, the charge consisted of just Big River, Debden and Rapid Bend.

Around 1972, Big River and Canwood (previously part of Shellbrook-Leask Pastoral Charge) amalgamated to form Big River - Canwood Pastoral Charge. Canwood's Trinity United Church closed March 30 2010, leaving just Big River's First United Church in the pastoral charge. As of April 27, 2012, the name returned to Big River Pastoral Charge.

Morse Pastoral Charge was formed as a new United Church charge in 1925, part of Swift Current Presbytery and consisting of Morse and Ernfold appointments. (Later addition Herbert also formed that year, as a separate Mission Field in the same presbytery, as had the augmented Chaplin Pastoral Charge, in Moose Jaw Presbytery.) Around 1946, Herbert was added to Morse Pastoral Charge. Chaplin joined the charge ca.1958 and it was renamed Morse-Chaplin Pastoral Charge. The name changed to Herbert-Morse-Chaplin Pastoral Charge, December 1, 1996. Herbert closed June 30, 2006. The remaining charge officially closed June 30, 2015.