Saskatoon St. Martin's Pastoral Charge was formed in the mid-1950s, part of Saskatoon Presbytery and consisting of St. Martin's United Church.

Saskatoon Third Avenue Pastoral Charge was formed as as a new United Church charge in 1925, under Saskatoon Presbytery. It closed June 30, 2018.

Wakaw Pastoral Charge was formed as a new United Church charge in 1925, part of Prince Albert Presbytery and consisting of preaching points at Wakaw and Domremy. By 1951, it had moved to Saskatoon Presbytery but before 1958, it had returned to Prince Albert Presbytery. By 1962 St. Benedict and Prud'homme had joined the charge, while Domremy had left. Around the 1970s, the charge combined with Aberdeen and Rosthern St. Andrew's to form TRI Pastoral Charge (Saskatoon Presbytery). TRI Pastoral charge was divided again July 1, 1994, and the separate Wakaw Pastoral Charge was re-established.

Wolseley Pastoral Charge was formed as a new United Church charge in 1925. Preaching points in the charge included St. James United Church (Wolseley) and Westfield. Sometime before 1960, the charge amalgamated with Sintaluta, forming the Wolseley-Sintaluta Pastoral Charge. The name reverted back to Wolseley Pastoral Charge on June 30, 2002, when the preaching point at Sintaluta was formally closed.

Woodrow Pastoral Charge was formed as a new United Church charge in 1925, containing preaching points at Woodrow and Sunbeam. By 1962, it consisted of Woodrow, Glenbain, Kincaid, and Meyronne. The charge dissolved ca.1969 and the Woodrow preaching point became joined Lafleche Pastoral Charge.

Alameda Pastoral Charge was formed as a new United Church charge in 1925, part of Estevan Presbytery and containing preaching points at Alameda, Douglaston and Dalesboro. In the 1950s, Alameda amalgamated with Frobisher to form Alameda-Frobisher Pastoral Charge, with preaching points at Alameda, Dalesboro, Frobisher, and Out-of-Sight. After the closure of the Frobisher preaching point, the charge returned to the name Alameda Pastoral Charge, August 29, 2007.

Cadillac-Neville-Vanguard Pastoral Charge was created around 1969, after the addition of the Cadillac preaching point to the Neville-Vanguard Pastoral Charge. Around 1996, the charge amalgamated with Aneriod Pastoral Charge, to create New Venture Pastoral Charge.

New Venture Pastoral Charge was organized April 8, 1995, from the amalgamation of Aneroid Pastoral Charge and Cadillac-Neville-Vanguard Pastoral Charge. Early preaching points included: Aneroid; St. Paul's United, Cadillac; Glencaid United, Kincaid; St. Paul's United, Neville; Ponteix; and Vanguard. Neville closed June 30, 2008. Aneroid closed April 30, 2012. By 2018, only Kincaid and Ponteix remained in the charge.

Lampman Pastoral Charge was formed as a new United Church charge in 1925, as part of Arcola Presbytery, with appointments at Lampman, Wierhill, and Morrisview. By 1951, the charge was served by a summer supply minister and consisted of Lampman, Browning and Kingsford. The charge closed ca.1966 and Lampman joined Macoun Pastoral Charge. Around 1969, Lampman became part of Kisbey Pastoral Charge.

Loreburn-Hawarden Pastoral Charge was formed around 1962(?) from a combination of previous charges. Preaching points included Bonnie View, Elbow, Hawarden, Loreburn, Strongfield, and South Sask. River Development. As of January 1, 2017, Elbow amalgamated with Loreburn to become Elbow-Loreburn.

Abernethy Presbytery was one of the original 16 presbyteries established by the first General Council of the United Church of Canada (June 1925), to be part of the new Saskatchewan Conference. Initial boundaries were based on the previous Abernethy Presbytery, which had been part of the Presbyterian Synod of Saskatchewan.

In 1953, the pastoral charges in Abernethy Presbytery were divided and moved to other presbyteries: Nokomis Pastoral Charge was added to Saskatoon Presbytery; other charges located west of Highway 35 were reassigned to Regina Presbytery; and the charges east of Highway 35 were moved to Yorkton Presbytery, which was re-named Abernethy-Yorkton Presbytery.

Arcola Presbytery was one of the original 16 presbyteries established by the first General Council of the United Church of Canada (June 1925), to be part of the new Saskatchewan Conference. Initial boundaries were based on the previous Arcola Presbytery, which had been part of the Presbyterian Synod of Saskatchewan. Prior to 1925, there had also been an Arcola District, in the Methodist Saskatchewan Conference.

In 1951, Arcola and Estevan Presbyteries amalgamated and became Arcola-Estevan Presbytery.

Souris Valley Presbytery was created from the amalgamation of Arcola-Estevan Presbytery with part of Assiniboia Presbytery (the other part joined Moose Jaw Presbytery), ca.1973.

In 2000, Saskatchewan Conference went from 10 presbyteries to 7, with each adopting a new name. Most pastoral charges from Souris Valley Presbytery became part of the new Twin Valleys Presbytery.

Shaunavon Presbytery was created from the split of Assiniboia Presbytery, in 1926. In 1951, the two were reunited under the original name Assiniboia Presbytery.

Wascana Presbytery was one of the 7 presbyteries of Saskatchewan Conference created in 2000. It was initially comprised of pastoral charges from the former Regina Presbytery. In January 2019, as part of a larger restructuring of the United Church of Canada, Wascana Presbytery was combined with Saskatchewan Conference and the other remaining presbyteries to become Region 4.