Qu’Appelle Presbytery was one of the original 16 presbyteries established by the first General Council of the United Church of Canada (June 1925), to be part of the new Saskatchewan Conference. Initial boundaries were based on the previous Qu’Appelle Presbytery, which had been part of the Presbyterian Synod of Saskatchewan.

In 2000, Saskatchewan Conference went from 10 presbyteries to 7, with each adopting a new name. Most pastoral charges from Qu’Appelle Presbytery became part of the new Twin Valleys Presbytery.

Grenfell Pastoral Charge was formed as a United Church charge in 1925, part of Qu'Appelle Presbytery. By 1951, the charge consisted of preaching points at Grenfell, Kirkfield, Rillington, Tetlock, and Weldon. As of 1962, the charge only contained Grenfell and Summerberry. The preaching point at Summerberry closed December 31, 1984.