Hafford Hospital was first built around 1922, by the Missionary Society of the Methodist Church. The first superintendent was the Rev. G. Dorey, who would later become Moderator of the United Church of Canada (successor to the Methodist Church in Canada). Dr. S.M. Scott was the first doctor to serve the hospital, followed by Dr. Rose, who was later joined by Dr. Paulson. The Hafford Hospital Ladies Aid Society, formed 1924, was involved in raising money to support hospital activities. After financial difficulties in the 1930s, the hospital was eventually closed, in 1941, due to lack of funds.

In 1946, the R.M. of Redberry and the Village of Hafford bought the building and its equipment from the Missionary Society, then re-opened it as the Hafford Union Hospital.